The BIOMAT 2012 Symposium will be the Twelfth International Symposium on Mathematical and Computational Biology to be organized by the BIOMAT Consortium, a non-profit organization of scientists from universities and research centres from many countries on five continents. The BIOMAT Consortium was founded in 2001, during the activities of the First BIOMAT Symposium in Rio de Janeiro, Brazil. Its fundamental mission is to promote the scientific exchange of knowledge in the interdisciplinary areas of Mathematical Biology, Biological Physics and the Mathematical Modelling of Biosystems as well as the enhancement of multidisciplinary scientific work on Latin America and other regions with developing countries worldwide. The works selected by the BIOMAT Referee Board and senior AdHoc referees, on abstract and full paper form have an acceptance level of 20%. The BIOMAT series of books is indexed by ISI - Web of Science, Scientific Proceedings Citation Index. The series is published by World Scientific Co. Pte. Ltd. and every chapter corresponding to an accepted paper has a DOI link number. The BIOMAT 2012 Symposium will be a fundamental opportunity for research students and young Post Docs to exchange scientific feedback with their colleagues from USA and Canada, in the best tradition of the BIOMAT Symposium Series.